Sophia Tang
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README.md
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@@ -26,7 +26,7 @@ In this experiment, we fine-tune the pre-trained **DNA enhancer MDM from DRAKES*
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In this experiment, we fine-tune the pre-trained **unconditional peptide SMILES MDM from PepTune** ([Tang et al. 2024](https://arxiv.org/abs/2412.17780))
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In this experiment, we fine-tune the pre-trained **unconditional peptide SMILES MDM from PepTune** ([Tang et al. 2024](https://arxiv.org/abs/2412.17780)) to optimize **multiple therapeutic properties**, including target protein binding affinity, solubility, non-hemolysis, non-fouling, and permeability. We show that one-shot generation from the fine-tuned policy outperforms inference-time multi-objective guidance, marking a significant advance over prior fine-tuning methods. Code and instructions to reproduce our results are provided in `/tr2d2-pep`.
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